GAPPS Repository

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Biobank of Pregnancy and Newborn Specimens and Data

"Having access to an established pregnancy biobank saves us tremendous time and money."  – Gregory A. Buck, PhD, principal investigator, Virginia Commonwealth University 

Submit a request for specimens and/or data via the online form.
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The GAPPS Repository is a standardized, widely-accessible collection of high-quality specimens linked to data from diverse populations of pregnant women. The repository supports research on normal and abnormal pregnancies, including how pregnancy affects maternal and child health after delivery, as well as fetal origins of diseases. The collection includes contributions from women representing a range of racial, ethnic, regional and socioeconomic backgrounds.

Prospective Collections
Researchers can use existing specimens and data or gain access to a diverse cohort of participants for their specific project aims.

What’s Collected
The GAPPS Repository Collection Schedule chart below provides an overview of when specimens are collected. Specimens include: 

Participants also complete comprehensive questionnaires during pregnancy and at their postpartum visits. Other data is collected from maternal and newborn medical records.

Widely Accessible Data
The GAPPS Repository is a data and specimen bank available to eligible investigators worldwide. Specimen requests are evaluated by the GAPPS Utilization Committee and must be approved by the Institutional Review Board. Researchers are responsible for recovery and shipping costs.

A Foundation for Discoveries

Laying a foundation for discoveries that will improve maternal, newborn and child health worldwide, the repository supports a wide variety of research areas including genetics, epidemiology and pathophysiology, as well as translational science and healthcare delivery.

The repository enables researchers to:

Protecting Participant Privacy
GAPPS maintains the highest standards of privacy and confidentiality. Repository materials are identified only by number, with participant names kept in protected files at each collection site.

Equipment and Storage
The Repository is housed at Seattle Children’s Research Institute in Seattle’s South Lake Union neighborhood. Its state-of-the-art lab equipment and storage facilities include:

Specimen Collection Kits
Ease of use, accuracy and participant privacy were the top considerations in developing GAPPS’ specimen collection kits. Each comprehensive pre-packaged kit of collection supplies is labeled with a unique kit ID number, rather than a name. The barcode number is tracked by the GAPPS Repository and encoded with an expiration date to ensure supplies are current. Specimen containers are pre-labeled at the repository with specimen ID numbers linked to the kit ID. At the collection site this number is then linked to a unique participant research number. To ensure privacy, no personal identification information is available to the repository.

Data Management
The GAPPS Repository data management system is a customized, centralized, web-based specimen-tracking system that enables a single view of multiple specimen types combined with specimen-related clinical and demographic data. This system tracks data from GAPPS collection sites and maintains audits of all activities, while meeting reporting and compliance requirements.

GAPPS Repository Collection Network
GAPPS Repository receives specimens from a growing network of collection sites. Launched in Washington State, GAPPS is working to expand this network across the nation and around the world.

“The development of the Global Action Agenda and the launch of the GAPPS Repository are critical steps toward our goal of saving millions of babies around the world” – Seattle Children’s CEO Dr. Thomas Hansen


Discover how our widely accessible biobank is helping scientists close the knowledge and solution gaps.

GAPPS Projects

Learn how GAPPS research and advocacy efforts are working to prevent preterm birth and stillbirth.

Ways to Help

Power research efforts to improve birth outcomes around the world. Join our donor community today.

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